MDAI (5,6-Methylenedioxy-2-aminoindane) is Unscheduled in the United States. It is a gray area in the law because it may be illegal and covered under the analog act.
Addictive Potential: Unknown
Emergency Room Visits Yearly: Unknown
Mandatory Minimum Sentence: Unknown
Mechanism of Action: Increases Serotonin
5,6-Methylenedioxy-2-aminoindane (MDAI), is a drug and research chemical developed in the 1990's by a team led by David E. Nichols at Purdue University. It acts as a non-neurotoxic and highly selective serotonin releasing agent in animals and a putative empathogen in humans.
The chemical structure of MDAI is indirectly derived from that of the illicit drug MDA, but the alpha-methyl group of the alkylamino amphetamine side chain has been bound back to the benzene nucleus to form an indane ring system, which changes its pharmacological properties substantially. This indane ring also changes the structure of the molecule. Some believe that it may change it enough that it may not be covered under the analog act.
Side Effects and Adverse Reactions:
Research chemicals are experimental chemicals that are not approved for human consumption. This is because not enough data exists currently about their side effects, adverse reactions, long term damage, addiction potential, etc. Although some people are willing to ingest research chemicals, it is not reasonable to assume that they are in any way safe to use recreationally.
The NeuroSoup Trip Guide - This e-book discusses: Set, Setting, and Preparation for a Trip, Tips for Tripsitters, Aspects of the Entheogenic Experience, Working with Difficult Experiences, and Integration. Adverse psychological reactions, like flashbacks and HPPD, may potentially be avoided with proper preparation before and integration after entheogenic journeys. Thus, this e-book serves the purpose of harm reduction education. For clarity, NeuroSoup does not advocate the use of illegal, quasi-legal, or legal drugs. All substances that affect the central nervous system (legal or illegal) can have side effects, adverse reactions, and negative interactions with other drugs. Abstinence is always the best way to protect one's health.